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In some cases, the drug is even used as a preventive measure in women at extremely high risk of developing hereditary breast cancer. The reason that steroids can cause hair loss is due to the mechanism that causes natural male pattern baldness. However, there has been surprisingly little work on the mechanism by which these suprapharmacologic doses exert their actions or on pharmacologic strategies to distinguish beneficial (anabolic) effects from pathologic side effects on brain and heart.

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